Synthesis of N-phtaloyl amino acid p-tert-butylcalix[4]arene esters
نویسندگان
چکیده
منابع مشابه
Synthesis of N-Phtaloyl Amino Acid p-tert-butylcalix[4]arene Esters
The chemistry of calixarenes has received increasing attention in the field of Supramolecular Chemistry, as this class of molecules offers a suitable platform for the synthesis of receptors for anions, cations and neutral molecules. Their structures allow acylation and alkylaton reactions of the phenolic groups. The conformation and degree of substitution of acylated products are related to the...
متن کاملN-to-C solid-phase peptide and peptide trifluoromethylketone synthesis using amino acid tert-butyl esters.
Solid-phase peptide synthesis in the N-to-C direction, opposite to the classical C-to-N direction of peptide synthesis, provides the synthetically versatile C-terminal carboxyl group for further modification into C-terminally modified peptide mimetics. These are of general interest as potential bioactive agents, particularly as protease inhibitors. Elaboration of peptide mimetics on the solid-p...
متن کاملComputer-assisted automated synthesis. III. Synthesis of substituted N-(carboxyalkyl) amino-acid tert-butyl ester derivatives
A versatile automated synthesis apparatus, equipped with a chemical artificial intelligence, was developed to prepare and isolate a wide variety of compounds. The apparatus was to the synthesis of substituted N-(carboxyalkyl)amino-acids. The apparatus [1,2] is composed of units for performing various tasks,for example reagent supply, reaction, purification and separation, each linked to a contr...
متن کاملA convenient synthesis of amino acid methyl esters.
A series of amino acid methyl ester hydrochlorides were prepared in good to excellent yields by the room temperature reaction of amino acids with methanol in the presence of trimethylchlorosilane. This method is not only compatible with natural amino acids, but also with other aromatic and aliphatic amino acids.
متن کاملSynthesis, characterisation and biological evaluation of N-(ferrocenyl)naphthoyl amino acid esters as anticancer agents.
A series of N-(ferrocenyl)naphthoyl amino acid esters 5-18 has been prepared by coupling ferrocenyl naphthoic acids 3-4 to alpha-amino acids and linear amino acids in the presence of N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC) and 1-hydroxybenzotriazole (HOBt). The compounds were fully characterised by a range of NMR spectroscopic techniques, UV-Vis spectroscopy, mass spe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the Brazilian Chemical Society
سال: 2001
ISSN: 0103-5053
DOI: 10.1590/s0103-50532001000200021